Real and Barcelona’s week 33 La Liga match-up comes immediately on the back of the teams’ Champions League quarter-final second legs.
Real Madrid are to host arch-rivals Barcelona on Sunday 23 April in the second El Clásico of the 2016/17 La Liga season.
The matchday 33 clash at the Santiago Bernabéu will close out a blockbuster week in which both sides are also in Champions League action.
Real are at home to Bayern Munich on Tuesday 18 in their last-eight second leg, with Barça’s return against Juventus played at the Camp Nou the following day.
Meanwhile, this weekend provides a potentially pivotal round in shaping the top four as Real Madrid face a tough trip, while Atletico Madrid host Sevilla.
Real Madrid might have been handed a tough draw in facing Bayern Munich in the Champions League quarter-finals, but they’ll be aware that their forthcoming trip will be amongst their biggest tests this season.
Bilbao are unbeaten at the San Mames since Barcelona left with a 1-0 triumph in the second weekend of the season, with the hosts winning 10 and drawing three since then.
Having safely booked their own quarter-final place, Atletico head into the clash five points behind their visitors and have regained their defensive steal with Jan Oblak back between the sticks, recording three successive clean sheets.
Their only two home loses this season have come at the hands of Real and Barcelona, while they’ll take further confidence from Sevilla’s modest tally of just three goals from their last four outings.
Barcelona will be hoping to take advantage of any slip-ups when they host rivals Valencia, having slipped two points behind leaders Real last time out.
The Barcelona boss has had a week to refocus his side for the clash and allowed the team a two-day break before recalling a fully-fit squad to training on Thursday, with Neymar re-joining the group after missing the Deportivo defeat.
They’ve dominated the head to head with Valencia, losing just two of their last 22 meetings, while Barca’s six successive wins at the Nou Camp makes it an even more daunting trip for Los Che, who have won just won of their last 10 away games.